PROLON® The Fasting Mimicking Diet

The New 5 Day Meal Programme

ProLon® is Fasting with food. ProLon® is a 5-Day Meal Programme that nourishes your body through scientifically developed, plant-based foods, while supporting regenerative and rejuvenating changes.

ProLon® meals come in 5 small boxes (one for each day) that include plant-based energy bars, soups, a variety of snacks, drinks and supplements, all studied and carefully designed to nourish your body and promote positive changes.


What Is ProLon®?

ProLon® provides the body with healthy, plant-based ingredients that have been scientifically demonstrated to deliver optimal nourishment while not activating the key pro-ageing pathways including the growth hormone, insulin and Insulin-like Growth Factor (IGF-1) pathways activated by normal diets. These hormones signal to the body that it has consumed significant levels of carbohydrates and proteins and can activate genes that accelerate the growth pathways, which also speed ageing and block regeneration/rejuvenation.

ProLon® is the first Fasting Mimicking and Enhancing Diet that provides you with a combination of foods and ingredients able to reprogramme the body into a regenerating and rejuvenating mode, resulting in long-term reduction of IGF-1, glucose and markers of inflammation and ageing, but only in subjects with high levels of these markers.

Cellular entry into a high protection and stress resistant mode.

Removal of damaged cells and tissues.

Self-repair through cellular regeneration and rejuvenation.

ProLon® The Fasting Mimicking Diet
How it works

Why Choose ProLon ®?

In the latest clinical trial conducted at the University of Southern California's (SC) Longevity Institute and Diabetes and Obesity Research Institute, 3 cycles of ProLon, 5 days per month over a 3-month period suggested the following significant effects at 1 week after the last cycle:

Decrease Weight & Body Fat
Stem Cell Regeneration
Maintain Glucose At Healthy Levels
Maintain CRP at Healthy Levels
Maintain Triglycerides at Healthy Levels
Maintain Blood Pressure At Healthy Levels
Preservation of Bone Density
Decrease In IGF (Ageing Marker)
Maintain Insulin Resistance At Healthy Levels
Maintain Cholesterol At Healthy Levels
Decrease Visceral Fat


ProLon® meals come in 5 small boxes (one for each day) that include plant-based energy bars, soups, a variety of snacks, drinks and supplements, all studied and carefully designed to nourish your body and promote positive changes.


ProLon® ingredients are plant-based and do not contain any additives, preservatices* or chemicals. The daily calorific intake with ProLon® is between 750 and 1,100 calories from healthy ingredients that maximise nourishment and provide a pleasant eating experience.


ProLon® market research and consumer panels demonstrated:

Very good taste
Convenient and easy day-by-day packaging
Minimal disruption to daily lifestyle

What is a Fasting Mimicking Diet? (FMD)

The Fasting Mimicking Diet, or FMD, is the first meal programme made of healthy natural ingredients that you consume for five days, during which your body does not recognise that it is eating and therefore remains in a fasting mode. In simple terms, it is fasting with food!

This nutiotional breakthrough was scientifically developed and clinically tested at the Longevity Institute at the University of Southern California. Let by Prof. Valter Longo, the USC Longevity Institute unites multidisciplinary ageing research approaches in order to enhance Human Helath span, the healthy part of life.

Diet benefits promote and maintain healthy levels of:

Fasting Glucose
C-reactive protein, a marker of inflammation
Insulin-like growth factor 1, a marker associated with increased mortality and DNA damage in human cells
Stem cells and regenerative markers

Professor Valter Longo
Edna M. Jones Professor of Gerontology Professor of Biological Sciences

Prof. Longo is the Director of the Longevity Institute at University of Southern California and the inventor of the Fasting Mimicking Diet (FMD) nutritechnology. He is considered by many to be the global leader in nutrition and ageing. Professor Longo discovered 20 years ago that two out of the three pathways caused cellular ageing. His research team then embarked on a journey to uncover an impactful intervention that slows or reverses biological ageing in order to delay the onset of age related chronic diseases. If you think about it, if Alzheimer's disease, Diabetes type 2, most cancers and most cardiovascular diseases appear at later age in life, it is because ageing is the catalyst of these diseases, and therefore optimizing the way we age increases Healthspan, the healthy part of human life prior to disease onset.

Professor Longo then proved that periodic fasting, done for several consecutive days, is a very powerful intervention that our body learned to naturally cope with by protecting and rejuvenating itself, both anti-ageing measures. Because it is difficult and risky nowadays to fast on water only, Professor Longo, under the sponsorship of the National Institute of Health, National Cancer Institute, and National Institute on Ageing, has developed a natural plant based meal program named Fasting Mimicking Diet (FMD) which imitates fasting while feeding the body. Professor Longo's work has been published in top scientific journals like Cell, Nature, Science, Journal of Translational Medicine, and covered by top global media like CNN, FOX, BBC, New York Timesm Washington Post, etc.

ProLon® Is now available in our Clinics!
Call us today on:
03333 202 858

ProLon®, who's it for?

ProLon® Is intended for use by healthy invdividuals who want to optimize their health and wellbeing, by overweight or obese individuals who want to manage their weight in an easy and healthy way, and by people who have well-known markers for chronic and unhleahty conditions. ProLon has been clinically proven to reduce multiple biomarkers for ageing and negative conditions such as abdominal fat, waist circumference, glucose, IGF-1, and CRP

The ProLon® dietary program required guidance from a healthcare provider, such as a dietitian or nurse practitioner, for healthy individuals or a physician for individuals at risk for side effects or presenting certain diseases.

Frequently Asked Questions

What is ProLon®?

ProLon® is the first Fasting Mimicking Diet™ (FMD™) developed to provide the beneficial effects of fasting by making the fasting mimicking period safe and pleasant. ProLon®, which contains plant-based soups, bars, crackers, olives, drinks, and supplements, is a proprietary 5-day dietary programme, providing approximately 750 to 1100 calories per day. It is based on innovative research carried out at two of the world’s leading centres for biomedical and longevity research located at the University of Southern California (USC), the Longevity Institute and the Diabetes and Obesity Research Institute. This revolutionary meal plan has been scientifically designed and clinically tested to mimic the effects of fasting, while providing the proper daily nourishment and the feeling of satisfaction.

Who should engage in the ProLon® dietary program?

ProLon® was shown in clinical trials to have beneficial effects on a wide variety of markers: it decreases abdominal fat while increasing relative lean body mass, decreases fasting glucose, reduces C-reactive protein (a marker of inflammation), and reduces IGF-1 (associated with increased DNA damage mortality and ageing in humans).

What does a "Fasting Mimicking" Diet mean?

A Fasting Mimicking™ Diet (FMD™) is a high nutrition, low protein, low carbohydrate meal plan, clinically proven to beneficially change a wide range of biomarkers associated with ageing, poor health, and inflammation. (See Question 2).

How should the ProLon® Diet be taken?

The diet should be followed for 5 consecutive days, after which the patient will transition for 1 day and then resume their normal diet. Instructions are provided in every carton. A specific combination of food is provided on each day for breakfast, lunch, dinner and snacks. All food provided on a specific day should be taken on that day only. While a meal missed can be made up at any time during the same day, there should be no carryover from one day to the next. The 5-day diet should be taken as often as is recommended by the healthcare professional.

How much weight does one lose and will the individual be able to keep it off?

The amount of weight loss varies by individual. A healthcare professional will be able to discuss this during consultation and work with the patient on meeting weight goals.

Can ProLon® be used by patients with a chronic illness or disease?

Depending on the medical illness or disease, past medical history, and current medications, the ProLon® dietary programme might be combined with the standard of care treatment; however, ProLon® cannot be prescribed to prevent or treat diseases. Contact the healthcare provider most familiar with the illness or disease to discuss the ProLon® dietary programme.

Should routine intake of supplements during the dieting period be stopped?

As the ProLon® dietary programme is designed to provide all of the supplements and nutrients needed, no additional multivitamins or supplements should be taken during the diet period; however, the options should be discussed with the supervising healthcare professional.

How many ProLon® cycles can be recommended to a patient in a year?

This depends on the patient’s baseline markers and health measurements, assessment and, where relevant, recommendation of the healthcare professional. For the majority of relatively healthy individuals, 3 to 4 times a year is sufficient. By contrast, for individuals with high levels of multiple biomarkers for ageing, cholesterol, IGF-1, CRP, blood pressure, abdominal fat, etc., the healthcare professional may decide to recommend 6-12 ProLon® cycles a year. For very high risk patients it may be given as often as every 15 days.

Once the patient starts the ProLon® cycle can they split up days?

Splitting up days is not recommended since this method is believed to be much less effective than the 5 consecutive days.

Is there a 'Transition Day' diet for the patient after completing the ProLon® diet?

On Day 6, after the ProLon® diet ends, users should avoid binge eating and resume their normal diet gradually. They should start with liquid foods, such as soups and fruit juices, followed by light meals, including rice, pasta and small portions of meat, fish and/or legumes. A normal diet can be resumed on day 7, or 24 hours after the end of the ProLon® diet.

Is there scientific data to prove the ProLon® dietary programme allows patients to reach a "fasting state"?

The results achieved with ProLon® in clinical trials were very similar to those achieved with fasting. However, ProLon® is safer, providing vital nutrition during the 5 day diet.

Is there scientific data supporting ProLon® ingredients and formulation?

The proprietary dietary formulation is based on decades of scientific research, including preclinical and clinical trials and contains specific ingredients that were put together to mimic fasting, while optimising nourishment.

Are all the components of the diet considered organic?

The meal plan contains some products that are made with organic ingredients, but they are not certified organic. Our food products are all plant-based.

What other foods can be consumed while on ProLon®?

As the ProLon® dietary programme provides everything needed for nourishment during the 5 days, while letting the powerful self-repair and rejuvenation mechanisms work, no extra foods or drinks (other than water and decaffeinated tea) should be consumed while on ProLon®, to avoid reducing its efficacy.

If extra calories throughout the day are needed, what can be consumed?

Nothing extra should be eaten while on the ProLon® dietary programme. Since this diet is low calorie, followers may experience the feeling of slight weakness and possible dizziness as the body adjusts, especially on Day 2. This is normal. Usually by Day 3 this decreases; however, should the symptoms be severe, fruit juices can be consumed and call your doctor or 999 for emergencies. The supervising healthcare professional should then review if it is safe for the patient to continue on the diet. The energy drink provided in the diet boxes, to be taken throughout the day, provides not only nutritional support during the diet, but can be specifically helpful in these instances.

What can patients do if they are very hungry during the 5 days?

Because the ProLon® diet is low in calories, hunger may occur during the 5-day diet period. Most clinical trial participants only experienced a low level of periodic hunger. In such cases, one may want to consume a food that is not highly caloric, such as a slice of an apple. Remember, this diet is only for 5 days. Feeling hungry is normal if one’s usual diet consists of high calories. People generally reported that the hunger subsided by Day 3 or 4.

Can coffee be consumed while on ProLon®?

Because coffee can interfere with the beneficial effects of the diet, it is not recommended to be consumed with ProLon®. However, for those who cannot go without, we recommend minimising coffee consumption to 1 cup per day.

Can different flavours of tea be substituted while on ProLon®?

There are different flavours of teas provided with the diet. Although not recommended, since the ProLon® teas are selected for specific properties and have been clinically tested, if for some reason one does not want to consume one of these flavours, a substitution can be made. A substitute tea should have no caffeine or additives, and should be taken without sugar or milk.

If all the food is not eaten for the day, is it ok?

Yes; however, since this diet has been clinically tested, one should make every effort to follow the programme precisely to minimise malnourishment and safety issues.

What if one meal is missed, can it be taken later on the same day?

This is not advised; the foods provided should only be consumed on the day for which they are designated. However, if the patient feels lightheaded, dizzy or has any other side effects, consuming one of the leftover diet foods would be preferable to consuming something else. Note: the ProLon® diet does not have extras in the meal box.

Can the diet be stopped at Day 4?

The positive effects of the ProLon® dietary programme tested in the clinical trials require 5 consecutive days. Therefore, the diet should be maintained for the full 5 days.

What if food outside the ProLon® diet was eaten during one day of the diet because of circumstances (e.g social events)

The diet is formulated based on specific nutritional, scientifically proven benefits. Therefore, it’s very important to follow the diet closely. However, if this happens on one occasion, do not worry —continue with the ProLon® dietary programme for the rest of the 5 days.

What are the options if certain ProLon® food items are disliked?

It depends on the food item. For example, if a soup is disliked, lemon/lime and herbs can be added in small quantities. If a tea is disliked, a different tea can be substituted, provided it is non-caffeinated, non-sugared, preferably with no added colour or preservatives.

Can fresh herbs be added to the soups?

Yes, herbs and lemon in small quantities may be added to taste. Please note that the diet is specially formulated to provide a specific amount of nutrients and calories.

What is DHA?

DHA stands for docosahexaenoic acid and is an omega-3 fatty acid. DHA is essential for normal brain function.

What is the energy drink for?

The energy drink is specially formulated to provide vegetable-based nutritional support during the diet.

What is the energy drink made from?

The energy drink is made from plant-derived glycerol and water. This selection is the result of years of studies to maximise safety and nourishment without interfering with the beneficial effects of the diet.

What is it in the food that makes it "anti-ageing"?

ProLon® is the first and only Periodic Fasting Mimicking Diet and is scientifically developed, and clinically proven to induce a fasting state which optimizes metabolic health and decreases age-related risk factors. The rejuvenation effect is the main reason why ProLon® followers lose fat very quickly while preserving lean body mass (muscle and bone).

Can I participate in this programme if I have a history of allergy or may be gluten - or lactose - sensitive?

ProLon® Fasting Mimicking Diet is Lactose and Gluten Free. Participants with food allergies such as nuts, soy, tomato, or with any other known allergies to the ingredients, should avoid consuming ProLon® or wait until a version of ProLon® is produced that is free of allergens.

What is the recommended "healthy" or "normal" daily calorific intake?

We recommend you discuss your ongoing diet with your GP. They can review your current intake and give you specific guidelines to follow based on your height, weight and gender. During the 5-Day ProLon® dietary programme, approximately 1100 calories are consumed on Day 1 and 750 calories on Days 2-5.

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